Adaptogen
Eleuthero
Also known as: Siberian Ginseng
An adaptogenic herb used to improve resilience to stress and support mental and physical endurance.
KÖGN Health grades Eleuthero as B (Moderate evidence) and rates it 3.8 out of 5.
Last reviewed · June 2026
Primary effects
- Reduced fatigue
- Improved resilience
- Enhanced endurance
How it works
Modulates stress response systems, improving resilience and reducing fatigue.
Overview
Eleuthero is a milder adaptogen compared to Panax Ginseng but is valued for its ability to support long-term stress adaptation. It works gradually, helping the body maintain balance under chronic stress rather than providing immediate stimulation. It is often used in combination with other adaptogens for a broader stress management strategy.
The evidence
Eleuthero (Eleutherococcus senticosus, 'Siberian ginseng') is an adaptogen traditionally used for fatigue and stamina. Human evidence is mixed: it is recommended by the European Medicines Agency for symptoms of asthenia, and combination adaptogen formulas have improved attention in tired people, but a controlled trial adding eleuthero to stress management found no benefit over the training alone. A plausible anti-fatigue herb with modest, inconsistent cognitive data.
How to dose it
Commonly used at roughly 300–1,200 mg/day of a standardised root extract, often in cycles.
When to take it
Both — single-dose adaptogen effects reported, alongside chronic use.
Safety & side effects
Generally well tolerated; it can be mildly stimulating, so late-day doses may disturb sleep.
Who should avoid it
Take care, and ask a clinician, if you have high blood pressure, take digoxin or anticoagulants, or have a hormone-sensitive condition. Avoid in pregnancy. Periodic breaks are traditional with adaptogens.
References
Related ingredients
Graded entries that target the same cognitive goals.
Categories
Draft — the dose, safety and evidence notes on this entry were prepared from the published literature and are pending editorial and clinical review.
Educational information, not medical advice. The evidence grade is KÖGN’s editorial assessment of published research, not a health claim. Speak to a qualified clinician before changing what you take.