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Eugeroic

Modafinil

A wakefulness-promoting compound used to enhance alertness and sustained cognitive performance.

Evidence gradeCross-checked · High
A+
WeakModerateStrong
4.7/ 5 rating

KÖGN Health grades Modafinil as A+ (Strong evidence) and rates it 4.7 out of 5.

Last reviewed · June 2026

CategorySynthetic · Eugeroic
AvailabilityPrescription

Primary effects

  • Increased alertness
  • Improved focus
  • Reduced fatigue
  • Sustained wakefulness

How it works

Modulates orexin and dopamine systems to promote wakefulness and prolonged cognitive endurance.

Overview

Modafinil is widely regarded as one of the most effective wakefulness-promoting agents available. It supports prolonged periods of cognitive performance without the typical crash associated with traditional stimulants. While highly effective, it is prescription-only in many regions and should be used responsibly due to potential side effects and individual variability in response.

Related ingredients

Graded entries that target the same cognitive goals.

Categories

Synthetic NootropicsEnergy & Mental StimulationFocus & AttentionStimulants (CNS Activation)Prescription-BasedAcute Performance NootropicsHigh Evidence

Educational information, not medical advice. The evidence grade is KÖGN’s editorial assessment of published research, not a health claim. Speak to a qualified clinician before changing what you take.