MAO-B Inhibitor
Selegiline
A compound that increases dopamine levels by inhibiting monoamine oxidase-B.
KÖGN Health grades Selegiline as A (Strong evidence) and rates it 4.3 out of 5.
Last reviewed · June 2026
Primary effects
- Improved motivation
- Enhanced focus
- Mood elevation
How it works
Increases dopamine availability, supporting mood, motivation, and cognitive function.
Overview
Selegiline is a prescription compound used in Parkinson’s disease and has been explored for cognitive and mood enhancement. By inhibiting MAO-B, it increases dopamine availability, which can enhance motivation and cognitive drive. Due to its potency and pharmacological nature, it should be used cautiously and under medical supervision.
Related ingredients
Graded entries that target the same cognitive goals.
Categories
Educational information, not medical advice. The evidence grade is KÖGN’s editorial assessment of published research, not a health claim. Speak to a qualified clinician before changing what you take.