Vitamin B1 Derivative
Sulbutiamine
A fat-soluble derivative of vitamin B1 used to support energy, motivation, and cognitive performance.
KÖGN Health grades Sulbutiamine as B+ (Moderate evidence) and rates it 4.0 out of 5.
Last reviewed · June 2026
Primary effects
- Increased energy
- Improved motivation
- Reduced fatigue
How it works
Increases thiamine levels in the brain, supporting energy metabolism and mental drive.
Overview
Sulbutiamine is a modified form of thiamine designed to cross the blood-brain barrier more efficiently. It is often used to reduce fatigue and enhance motivation, particularly in states of low energy or burnout. Its effects are typically noticeable but can diminish with continuous use, making cycling beneficial.
Related ingredients
Graded entries that target the same cognitive goals.
Categories
Educational information, not medical advice. The evidence grade is KÖGN’s editorial assessment of published research, not a health claim. Speak to a qualified clinician before changing what you take.