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Vitamin

Vitamin B9

Also known as: Folate, L-Methylfolate

An essential vitamin required for DNA synthesis, brain development, and neurotransmitter function.

Evidence gradeCross-checked · High
A+
WeakModerateStrong
4.5/ 5 rating

KÖGN Health grades Vitamin B9 as A+ (Strong evidence) and rates it 4.5 out of 5.

Last reviewed · June 2026

CategoryNutritional · Vitamin
AvailabilityOTC

Primary effects

  • Mood support
  • Cognitive clarity
  • Brain health

How it works

Supports methylation and neurotransmitter production, influencing mood and cognitive function.

Overview

Vitamin B9 in its active form (L-methylfolate) is critical for neurological function and methylation processes. It plays a key role in neurotransmitter synthesis and has been strongly linked to mood regulation. Deficiency is associated with cognitive decline and mood disorders, making it essential for long-term brain health and stability.

Related ingredients

Graded entries that target the same cognitive goals.

Categories

Nutritional NootropicsMood & Emotional RegulationBrain Energy & MetabolismSerotonergics (Serotonin Support)Daily Foundational NootropicsOver-the-Counter (OTC)High Evidence

Educational information, not medical advice. The evidence grade is KÖGN’s editorial assessment of published research, not a health claim. Speak to a qualified clinician before changing what you take.