Adrenergic Stimulant
Yohimbine
A stimulant compound that increases alertness, energy, and focus under certain conditions.
KÖGN Health grades Yohimbine as B (Moderate evidence) and rates it 3.9 out of 5.
Last reviewed · June 2026
Primary effects
- Increased alertness
- Energy boost
- Enhanced focus
How it works
Blocks alpha-2 adrenergic receptors, increasing norepinephrine activity.
Overview
Yohimbine is a potent stimulant that increases norepinephrine activity, leading to heightened alertness and energy. However, it can also increase anxiety, heart rate, and stress response, making it less suitable for sensitive individuals. It is typically used in short-term or targeted performance contexts rather than daily cognitive support.
Related ingredients
Graded entries that target the same cognitive goals.
Categories
Educational information, not medical advice. The evidence grade is KÖGN’s editorial assessment of published research, not a health claim. Speak to a qualified clinician before changing what you take.