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Polyphenol

Curcumin

An active compound in turmeric known for its anti-inflammatory and neuroprotective effects.

Evidence gradeCross-checked · High
A
WeakModerateStrong
4.0/ 5 rating

KÖGN Health grades Curcumin as A (Strong evidence) and rates it 4.0 out of 5.

Last reviewed · June 2026

CategoryNatural · Polyphenol
AvailabilityOTC

Primary effects

  • Reduced inflammation
  • Neuroprotection
  • Improved mood

How it works

Reduces inflammation and oxidative stress, supporting long-term brain health.

Overview

Curcumin has strong evidence supporting its anti-inflammatory and antioxidant properties, both of which are critical for long-term cognitive health. However, its bioavailability is naturally low, meaning it is most effective when paired with absorption enhancers such as piperine. It does not provide immediate cognitive enhancement but plays a significant role in protecting against cognitive decline over time.

Related ingredients

Graded entries that target the same cognitive goals.

Categories

Natural NootropicsNeuroprotection & LongevityAnti-Inflammatory CompoundsAntioxidants (Oxidative Stress Reduction)Long-Term Cognitive SupportOver-the-Counter (OTC)High Evidence

Educational information, not medical advice. The evidence grade is KÖGN’s editorial assessment of published research, not a health claim. Speak to a qualified clinician before changing what you take.