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Omega-3 Fatty Acid

EPA

Also known as: Eicosapentaenoic Acid

An omega-3 fatty acid known for its role in mood regulation and inflammation control.

Evidence gradeCross-checked · High
A+
WeakModerateStrong
4.4/ 5 rating

KÖGN Health grades EPA as A+ (Strong evidence) and rates it 4.4 out of 5.

Last reviewed · June 2026

CategoryNutritional · Omega-3 Fatty Acid
AvailabilityOTC

Primary effects

  • Improved mood
  • Reduced inflammation
  • Cognitive support

How it works

Reduces inflammation and supports neurotransmitter function linked to mood and cognition.

Overview

EPA is particularly effective for mood and emotional regulation, often showing stronger effects than DHA in this area. It plays a key role in reducing systemic inflammation, which is increasingly linked to cognitive decline and mental health issues. It is typically consumed alongside DHA as part of a balanced omega-3 intake.

Related ingredients

Graded entries that target the same cognitive goals.

Categories

Nutritional NootropicsMood & Emotional RegulationNeuroprotection & LongevityAnti-Inflammatory CompoundsDaily Foundational NootropicsOver-the-Counter (OTC)High Evidence

Educational information, not medical advice. The evidence grade is KÖGN’s editorial assessment of published research, not a health claim. Speak to a qualified clinician before changing what you take.