Amino Acid Derivative
N-Acetylcysteine
Also known as: NAC
A precursor to glutathione that supports antioxidant defence, brain health, and mood regulation.
KÖGN Health grades N-Acetylcysteine as A (Strong evidence) and rates it 4.3 out of 5.
Last reviewed · June 2026
Primary effects
- Neuroprotection
- Improved mood
- Reduced oxidative stress
How it works
Boosts glutathione levels, reducing oxidative stress and supporting neurotransmitter balance.
Overview
NAC is widely studied for its role in supporting glutathione, one of the body’s primary antioxidant systems. It has also been explored for its effects on mood regulation and compulsive behaviours through glutamate modulation. Its benefits are more long-term and systemic rather than immediately cognitive, making it a foundational health-support compound.
Related ingredients
Graded entries that target the same cognitive goals.
Categories
Educational information, not medical advice. The evidence grade is KÖGN’s editorial assessment of published research, not a health claim. Speak to a qualified clinician before changing what you take.