Flavonoid
Kaempferol
A plant-derived antioxidant with potential neuroprotective and anti-inflammatory properties.
KÖGN Health grades Kaempferol as C+ (Limited evidence) and rates it 3.5 out of 5.
Last reviewed · June 2026
Primary effects
- Neuroprotection
- Reduced inflammation
- Cognitive support
How it works
Reduces oxidative stress and inflammation, supporting long-term brain health.
Overview
Kaempferol is a flavonoid found in various fruits and vegetables, studied primarily for its antioxidant and anti-inflammatory effects. While promising in cellular and animal models, human research on cognitive outcomes is limited. Its role is primarily supportive, contributing to long-term brain health rather than immediate cognitive enhancement.
The evidence
Kaempferol is a dietary flavonoid (found in kale, beans, tea and many plants) with antioxidant and anti-inflammatory activity. Its cognitive interest is preclinical — neuroprotection in cell and animal models — with essentially no controlled human cognition trials. Any nootropic claim is an extrapolation from lab work and general flavonoid epidemiology.
How to dose it
There is no established human dose for cognition; intake mainly comes from a plant-rich diet rather than isolated supplements.
When to take it
Chronic — dietary, long-term.
Safety & side effects
Considered safe at dietary levels; concentrated-supplement safety is poorly characterised.
Who should avoid it
Few specifics at dietary intake. As with other flavonoids, concentrated doses could affect drug-metabolising enzymes — check with a clinician if you take medication. Evidence is preclinical.
References
Related ingredients
Graded entries that target the same cognitive goals.
Categories
Draft — the dose, safety and evidence notes on this entry were prepared from the published literature and are pending editorial and clinical review.
Educational information, not medical advice. The evidence grade is KÖGN’s editorial assessment of published research, not a health claim. Speak to a qualified clinician before changing what you take.