Coenzyme
NAD+
Also known as: Nicotinamide Adenine Dinucleotide
A critical coenzyme involved in cellular energy production and ageing processes.
KÖGN Health grades NAD+ as A (Strong evidence) and rates it 4.2 out of 5.
Last reviewed · June 2026
Primary effects
- Increased cellular energy
- Neuroprotection
- Anti-ageing support
How it works
Plays a central role in mitochondrial energy production and cellular repair processes.
Overview
NAD+ is essential for energy metabolism and cellular repair, and levels naturally decline with age. While direct supplementation is limited in effectiveness due to bioavailability, precursors such as NMN or NR are often used instead. Its cognitive relevance is tied to mitochondrial function and long-term brain health rather than acute performance enhancement.
Related ingredients
Graded entries that target the same cognitive goals.
Categories
Educational information, not medical advice. The evidence grade is KÖGN’s editorial assessment of published research, not a health claim. Speak to a qualified clinician before changing what you take.