Beta-Blocker
Propranolol
Also known as: Off-label cognitive use
A beta-blocker sometimes used off-label to reduce performance anxiety and stress response.
KÖGN Health grades Propranolol as A (Strong evidence) and rates it 4.0 out of 5.
Last reviewed · June 2026
Primary effects
- Reduced anxiety
- Improved performance under stress
How it works
Blocks adrenergic activity, reducing physical symptoms of anxiety under pressure.
Overview
Propranolol is primarily a cardiovascular medication, but it is sometimes used off-label for performance anxiety, particularly in high-pressure situations such as public speaking. It does not enhance cognition directly but can indirectly improve performance by reducing physiological stress responses. It should be used cautiously and under appropriate medical guidance.
Related ingredients
Graded entries that target the same cognitive goals.
Categories
Educational information, not medical advice. The evidence grade is KÖGN’s editorial assessment of published research, not a health claim. Speak to a qualified clinician before changing what you take.