Vitamin B6 Derivative
Pyritinol
A semi-synthetic compound derived from vitamin B6 used to support cognition and cerebral metabolism.
KÖGN Health grades Pyritinol as B (Moderate evidence) and rates it 3.8 out of 5.
Last reviewed · June 2026
Primary effects
- Improved memory
- Increased mental energy
- Cognitive support
How it works
Improves glucose utilisation in the brain and may support cognitive efficiency under stress.
Overview
Pyritinol has been studied for its potential effects on cognitive performance, particularly in ageing populations and conditions involving reduced cerebral metabolism. While some studies suggest modest benefits, the evidence is mixed and not as strong as more established nootropics. It is generally considered a mild cognitive enhancer rather than a core foundational compound.
Related ingredients
Graded entries that target the same cognitive goals.
Categories
Educational information, not medical advice. The evidence grade is KÖGN’s editorial assessment of published research, not a health claim. Speak to a qualified clinician before changing what you take.