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Bile Acid Derivative

Tauroursodeoxycholic Acid

Also known as: TUDCA

A bile acid derivative that supports cellular health, mitochondrial function, and neuroprotection.

Evidence gradeCross-checked · Emerging
B+
WeakModerateStrong
4.1/ 5 rating

KÖGN Health grades Tauroursodeoxycholic Acid as B+ (Moderate evidence) and rates it 4.1 out of 5.

Last reviewed · June 2026

CategoryNatural · Bile Acid Derivative
AvailabilityOTC

Primary effects

  • Neuroprotection
  • Improved cellular resilience
  • Reduced stress

How it works

Reduces cellular stress and supports mitochondrial and endoplasmic reticulum function.

Overview

TUDCA is primarily studied for its role in liver and cellular health, but emerging research suggests it may also support brain health through its neuroprotective and anti-apoptotic properties. It helps reduce cellular stress and may improve mitochondrial efficiency, which is important for long-term cognitive resilience. Human research in cognition is still limited but promising.

Related ingredients

Graded entries that target the same cognitive goals.

Categories

Natural NootropicsNeuroprotection & LongevityBrain Energy & MetabolismCellular SupportLong-Term Cognitive SupportOver-the-Counter (OTC)Emerging Evidence

Educational information, not medical advice. The evidence grade is KÖGN’s editorial assessment of published research, not a health claim. Speak to a qualified clinician before changing what you take.