Flavonoid
Apigenin
A plant-derived compound with calming, anti-inflammatory, and neuroprotective properties.
KÖGN Health grades Apigenin as B (Moderate evidence) and rates it 3.8 out of 5.
Last reviewed · June 2026
Primary effects
- Reduced anxiety
- Improved relaxation
- Sleep support
- Neuroprotection
How it works
Modulates GABA activity and reduces inflammation, supporting relaxation and cognitive recovery.
Overview
Apigenin is commonly found in chamomile and is often used for its calming and sleep-supportive effects. It works primarily through GABAergic pathways, promoting relaxation without heavy sedation. While its direct cognitive enhancement effects are limited, it plays a valuable role in recovery and stress management, which indirectly supports performance. It is often included in evening protocols or stacks focused on sleep quality.
Related ingredients
Graded entries that target the same cognitive goals.
Categories
Educational information, not medical advice. The evidence grade is KÖGN’s editorial assessment of published research, not a health claim. Speak to a qualified clinician before changing what you take.