Neurotransmitter
GABA
Also known as: Gamma-Aminobutyric Acid
The primary inhibitory neurotransmitter responsible for reducing neuronal excitability and promoting calmness.
KÖGN Health grades GABA as B (Moderate evidence) and rates it 3.7 out of 5.
Last reviewed · June 2026
Primary effects
- Reduced anxiety
- Improved relaxation
- Stress reduction
How it works
Reduces neural activity, promoting relaxation and reducing stress.
Overview
GABA plays a central role in calming the nervous system, but oral supplementation has limited ability to cross the blood-brain barrier. As a result, its direct cognitive effects may be less pronounced than expected. However, it can still support relaxation and stress reduction indirectly, particularly when combined with other compounds that enhance its activity.
Related ingredients
Graded entries that target the same cognitive goals.
Categories
Educational information, not medical advice. The evidence grade is KÖGN’s editorial assessment of published research, not a health claim. Speak to a qualified clinician before changing what you take.