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Herbal Extract

Kava

A plant extract known for its strong anxiolytic and calming effects.

Evidence gradeCross-checked · Moderate-high
B+
WeakModerateStrong
4.0/ 5 rating

KÖGN Health grades Kava as B+ (Moderate evidence) and rates it 4.0 out of 5.

Last reviewed · June 2026

CategoryNatural · Herbal Extract
Typical doseAnxiety trials commonly use extracts standardised to 'kavalactones', often around 120–240 mg of kavalactones per day, for short periods.
AvailabilityOTC

Primary effects

  • Reduced anxiety
  • Relaxation
  • Stress relief

How it works

Modulates GABA activity, reducing anxiety and promoting relaxation.

Overview

Kava is highly effective for reducing anxiety and promoting relaxation, often producing noticeable effects shortly after use. However, it is typically used occasionally rather than daily due to potential concerns around liver health with excessive or prolonged use. It is best suited for situational stress or anxiety management.

The evidence

Kava (Piper methysticum) is an anxiety remedy, not a focus aid. Meta-analyses of randomised trials find kava extracts reduce anxiety symptoms more than placebo, though more recent, larger trials have been less convincing. Any cognitive relevance is indirect — calmer, less anxious thinking — and at higher doses kava is sedating.

How to dose it

Anxiety trials commonly use extracts standardised to 'kavalactones', often around 120–240 mg of kavalactones per day, for short periods.

When to take it

Both — acute calming, with anxiety trials run over a few weeks.

Safety & side effects

Can cause drowsiness; the serious concern is liver toxicity. Rare but real cases of severe liver injury have been reported, which is why several countries restricted it.

Who should avoid it

Avoid kava if you have liver disease, drink alcohol heavily, or take medication that affects the liver, and do not use it for more than a few weeks without medical oversight. Do not combine with sedatives, and avoid before driving. Not for use in pregnancy.

References

Related ingredients

Graded entries that target the same cognitive goals.

Categories

Natural NootropicsStress & Anxiety ReductionMood & Emotional RegulationGABAergics (Calming / Inhibitory Support)Acute Performance NootropicsOver-the-Counter (OTC)Moderate-High Evidence

Draft — the dose, safety and evidence notes on this entry were prepared from the published literature and are pending editorial and clinical review.

Educational information, not medical advice. The evidence grade is KÖGN’s editorial assessment of published research, not a health claim. Speak to a qualified clinician before changing what you take.