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Adaptogen

Withania Somnifera

Also known as: Ashwagandha

A traditional Ayurvedic adaptogen used to reduce stress and support cognitive resilience.

Evidence gradeCross-checked · High
A
WeakModerateStrong
4.3/ 5 rating

KÖGN Health grades Withania Somnifera as A (Strong evidence) and rates it 4.3 out of 5.

Last reviewed · June 2026

CategoryNatural · Adaptogen
AvailabilityOTC

Primary effects

  • Reduced stress
  • Improved mood
  • Enhanced resilience

How it works

Reduces cortisol and supports stress adaptation, improving mood and cognitive stability.

Overview

Ashwagandha is one of the most well-researched adaptogens, with strong evidence supporting its ability to reduce stress and anxiety. It works by modulating the hypothalamic-pituitary-adrenal (HPA) axis, helping the body manage chronic stress more effectively. Its benefits are cumulative and become more noticeable with consistent use over time.

Related ingredients

Graded entries that target the same cognitive goals.

Categories

Natural NootropicsStress & Anxiety ReductionMood & Emotional RegulationAdaptogens (Stress Response Modulation)Long-Term Cognitive SupportOver-the-Counter (OTC)High Evidence

Educational information, not medical advice. The evidence grade is KÖGN’s editorial assessment of published research, not a health claim. Speak to a qualified clinician before changing what you take.